Aortic Stenosis and Mitral Regurgitation: Takeaways From the Heart Valve Collaboratory Workshop on Multivalvular Disease
This paper highlights unresolved clinical questions and proposes a research agenda focused on concomitant aortic stenosis and mitral regurgitation.
Transcatheter heart valve explantation for transcatheter aortic valve replacement failure: A Heart Valve Collaboratory expert consensus document on operative techniques
This expert consensus document reviews the current state of transcatheter valve replacement-explant with a specific focus on technical considerations, preoperative planning, and future directions in the field.
Imaging Methods for Evaluation of Chronic Aortic Regurgitation in Adults: JACC State-of-the-Art Review
This state-of-the-art review focuses on multi-modality assessment tools for aortic regurgitation severity and analyzes evolving data on the optimal timing of aortic valve intervention.
Clinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future
This review summarizes available data and knowledge gaps regarding procedural therapy for bicuspid aortic valve disease (BAVD), outlines specific challenges for trials, proposes potential studies that could be performed and presents a roadmap for future directions in clinical research in valve replacement for BAVD.
Standardized Definitions for Bioprosthetic Valve Dysfunction Following Aortic or Mitral Valve Replacement: JACC State-of-the-Art Review
This state-of-the-art review proposes standardized definitions for nonstructural and structural bioprosthetic valve dysfunction and valve failure following aortic or mitral biological valve replacement with the goal of facilitating research reporting and implementation of these terms in clinical practice.
Bioprosthetic Aortic Valve Hemodynamics: Definitions, Outcomes, and Evidence Gaps: JACC State-of-the-Art Review
This state-of-the-art review identifies areas of expert consensus, areas of disagreement, and evidence gaps related to bioprosthetic aortic valve hemodynamics.
Minimum Core Data Elements for Evaluation of TAVR: A Scientific Statement by PASSION CV, HVC, and TVT Registry
This systematic review of the published research for high-impact transaortic valve replacement (TAVR) studies and U.S. multicenter, multidevice registries resulted in 132 interoperable, reusable essential core data elements essential to supporting more efficient, consistent, and informative TAVR device evidence.
Evaluating Medical Therapy for Calcific Aortic Stenosis: JACC State-of-the-Art Review
This review briefly discusses the pathobiology and most promising pharmacologic targets, screening, diagnosis and progression of aortic stenosis, identification of subgroups that should be targeted in clinical trials, and the need to elicit the patient voice earlier rather than later in clinical trial design and implementation.
Reintervention after TAVR: Redo TAVR and TAVR Explant Workshop [Sneak Peek]

Why Study Reintervention after TAVR? Case presentations